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. Author manuscript; available in PMC: 2017 Dec 1.
Published in final edited form as: Cancer Immunol Res. 2016 Nov 1;4(12):1016–1026. doi: 10.1158/2326-6066.CIR-16-0159

Figure 6.

Figure 6

Human IL2c influences human immune cells. (A) Human lymphocytes were distinguished from murine cells by expression of human CD45. Flow plots show (B) CD8+ T cells and (C) CD4+ T cells, and inset numbers are the percent of total human CD45+ cells. (D) Tregs were distinguished by Foxp3 and CD25 expression, and inset number is the percent of total human CD45+ CD4+ cells. (E) Frequency of CD8+ and CD4+ T cells expressing T-bet or Foxp3 in (E) spleen and (F) tumor was assessed by intracellular flow cytometry. Data are pooled from 5 independent experiments for spleen and 3 for tumor.