Table 1.

Clinico-pathological annotations of renal cell carcinoma (RCC) samples selected in our study. All cases have been assessed for DNA methylation using DREAM technique. The details of sequencing tags and the read coverage are reported for DREAM. Selected RCC cases assessed by RNAseq are also specified.

Histology	Sample-ID	sexe	TNM pathological stage	Total number of tags	RNAseq	Nb of CpG sites with at least 10 tags coverage per site	Nb of CpG sites with at least 100 tags coverage per site
MITF/TFE translocation RCC	T1	F	T4N2M1	85 062 596	Yes	65 050	43 590
	T2	M	T1N2M1	75 410 891	no	98 341	38456
	T3	M	T3bN0M0	71422259	no	139 443	44 191
	T24	F	T3aN0M0	99 019 782	no	162226	43 215
	T34	M	T3bN1M0	57537059	yes	158229	44375
Clear-cell RCC	T11	F	T2N0M0	118 594 689	yes	156 156	42 552
	T12	M	T2N0M0	42 845 148	no	53 989	33 982
	T15	F	T1bN0M0	86725973	no	65104	40630
Papillary RCC (Type I)	T14	M	T1aN0M0	80 878 268	no	57 256	46 228
	T20	M	T2aNxM0	125 615 959	yes	59059	42120
	T21	M	T4N1M0	91521140	yes	118971	45886
Papillary RCC (Type II)	T7	M	T1bN0M0	78 384 802	no	151 757	37 930
	T8	F	T3bN2M0	77404215	no	54928	45572
Muscinous and spindle cell RCC	T13	M	T1N0M0	51 426 774	no	148 280	44 584
	T19	F	T1bNxM0	27216549	yes	51127	38557
Sarcomatoid RCC	T22	F	T4N1M1	59 402 641	no	121837	46 118
	T23	M	T4N1M0	140885594	no	98104	44956
Oncocytoma	T45	M	T1aNxM0	79 100 507	yes	82 991	36 167
	T46	F	T1aNxM0	77335441	yes	87629	46205
chromophobe	T10	F	T2N0M0	82 187 775	yes	61 940	61 940
	T16	M	T2aNxM0	73 994 602	yes	78 618	45 828
	T17	F	T1bNxM0	38917059	yes	51653	34117
Normal	N4	F		87 459 889	yes	76 348	43 590
	N8	F		84567697	yes	61256	41514