Table 1.
Information of the Toxoplasma gondii (T. gondii) infected women with recurrent spontaneous abortion (RSA)
| PatientNo. | Age (Y) CityProvince | Number of gestations (G),Number of abortions (AB) | Week of abortion | Chromosomal aneuploidies§ | Pathological findings in fetoplacental tissues | Symptoms |
|---|---|---|---|---|---|---|
| 1 | 36 Abhar Zanjan | G6, AB6All pregnancies aborted at second trimester | LMP†: 16w(Second trimester) | Not detected | Inflammatory cell infiltration with patchy amnionic necrotizing foci in the membrane | Fever, severe abdominal and back pain,premature rupture of membranes (PPROM) |
| 2 | 31 Tuyserkan Hamedan | G4, AB4All pregnancies aborted at first trimester | LMP: 11w+2dUltrasound: 8w(First trimester) | Not detected | No remarkable pathological findings | Hypothyroidism |
| 3 | 39 Eslamshahr Tehran | G8, AB8All pregnancies aborted at first trimester | LMP: 7w(First trimester) | Not detected | No remarkable pathological findings | No specific symptoms |
| 4 | 38 Tehran Tehran | G2, AB1She has one healthy girl | LMP: 11w(First trimester) | Not detected | No remarkable pathological findings | Rapid heartbeat, anemia andedema of the legs and ankles |
| 5 | 36 Karaj Alborz | G3, AB3All pregnancies aborted at first trimester. | Ultrasound: 6w+4d(First trimester) | MLPA findings compatible with an extra copy of chromosome 15 (trisomy 15) | The membrane showed calcification without inflammation | No specific symptoms |
| 6 | 28 Kashan Isfahan | G5, AB5 | LMP: 13wUltrasound: 11w(First trimester) | Not detected | No remarkable pathological findings | No specific symptoms |
| 7 | 31 Tehran Tehran | G3, AB3All pregnancies aborted at first trimester | LMP: 11wUltrasound: 8w+3d(First trimester) | Not detected | No remarkable pathological findings | No specific symptoms |
| 8 | 29 Tehran Tehran | G2, AB2All pregnancies aborted at first trimester | LMP: 11wUltrasound: 8w(First trimester) | Not detected | No remarkable pathological findings | No specific symptoms |
†; LMP: Last menstrual period and §; Chromosomal aneuploidies were detected using multiplex ligation-dependent probe amplification (MLPA).