Table 4.
Antimicrobial Activity of Isolated Compounds from Alternaria Sp. and Pyrenochaeta sp.a
| sample | MIC S. aureus | MIC MRSA | ||
|---|---|---|---|---|
| μM | μg/mL | μM | μg/mL | |
| berberine (+ control) | 446 | 150 | 446 | 150 |
| alternariol monomethyl ether (1) | 275 | 75 | NDb | ND |
| altersetin (3) | 0.59 | 0.23 | 4.67 | 1.9 |
| macrosphelide A (4) | 219 | 75 | ND | ND |
a
Minimum inhibitory concentrations (MIC) against S. aureus strain SA1199 and a strain of MRSA (USA300 LAC strain AH1263) are presented as mean of triplicate analyses. Berberine functioned as the positive control.
b
ND - not detected