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. 2016 Dec 2;22:1361–1374.

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Copyright © 2016 Molecular Vision.

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited, used for non-commercial purposes, and is not altered or transformed.

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PKR promotes tube formation of RF/6A cells in a coculture system under hypoxic conditions. A: Microscopic images showing tube formation in each group: normal, hypoxic, scramble siRNA, and dsRNA-activated protein kinase (PKR) siRNA. Representative photographs of tube formation of RF/6A cells (200× magnification). B: Decreased tube formation was observed when the cocultured RF/6A cells were transfected with PKR siRNA under hypoxia. *p<0.01, PKR siRNA group versus the hypoxia group. Values represent means ± SD.