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. 2016 Dec 2;22:1361–1374.

Figure 6.

Figure 6

PKR, p-PI3K, p-Akt, and VEGF expression is upregulated in a mouse CNV model. The mouse choroidal neovascularization (CNV) model was created with laser photocoagulation. A: DsRNA-activated protein kinase (PKR), phosphophosphatidylinositol 3-kinase (p-PI3K), phosphoprotein kinase B (p-Akt), and vascular endothelial growth factor (VEGF) protein levels were detected with western blotting. GAPDH was used as the loading control. B: The histogram shows the densitometric analysis of the average levels of PKR, p-PI3K, p-Akt, and VEGF to GAPDH. *p<0.05, statistically significantly different from the normal control. Values represent means ± SD.