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. 2016 Dec 3;7:64. doi: 10.1186/s13293-016-0111-9

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© The Author(s). 2016

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 2 — Inflammatory markers. Immunohistochemistry on the left sectioned kidney shows CD3 (a) and ED1 (b) inflammatory markers expressed as positive cells per glomerulus of the kidney. CD3, a T cell marker, was increased in the glomeruli at 6 months compared to that of 12 and 18 months of age, P < 0.01. ED1, a monocyte and macrophage marker, was increased in the glomeruli at 6 months compared to that of 12 and 18 months of age, P < 0.01. There were no influences of gonadectomy. Data are presented as mean ± SEM for n = 8 per group, ***P < 0.001