Table 2.
Characteristics of the 32 discovery cohort patients evaluated with musculoskeletal ultrasonography
| Anti-CCP-positive (n = 16) |
Anti-CCP-negative (n = 16) |
P value | |
|---|---|---|---|
| Age, years, median | 58 | 58 | N.S. |
| Disease duration, years, median | 10.5 | 10.5 | N.S. |
| Female, number | 14 | 13 | N.S. |
| Fulfilled ACR-82 criteria number, median | 4 | 4 | N.S. |
| Meeting arthritis criterion according to ACR-82, number | 13 | 14 | N.S. |
| Meeting nephritis criterion according to ACR-82, number | 4 | 2 | N.S. |
| Conventional radiographs available (hands/wrists/feet) | 16 | 16 | N.S. |
| Erosions on radiography, number of individuals | 4 | 0 | N.S. |
| HAQ score, median | 0.5 | 0.19 | N.S. |
| Ever smoker, number of individuals | 9 | 3 | N.S. |
| Rheumatoid factor positive, number of individuals | 6 | 1 | N.S. |
| anti-CarP antibody level, median | 275 | 102 | 0.04 |
| anti-CarP positive, number of individuals | 6 | 1 | N.S. |
| Daily dosage of prednisolone, median | 2.5 | 2.5 | N.S. |
ACR American College of Rheumatology, HAQ health assessment questionnaire, anti-CarP antibodies targeting carbamylated proteins, N.S. not significant