Table 6.

MID in case of deterioration and improvement of HRQOL for both QLQ-C30 and QLQ-BR23 questionnaires after three and six months

	Deterioration of HRQOL		Improvement of HRQOL
	Observed changes	Adjusted changes	Observed changes	Adjusted changes
QLQ-BR23 QLQ - C30
After 3 months	5–26	8–19	0.3–10	0.6–4
After 6 months	0.5–10	4–18	0.8–7	0–7
After 3 months	7–20	7–18	2–15	0–7
After 6 months	0.4–4	6–11	0.7–2	0–4