Table 1.
List of known CSPGs identified in the rVAR2 pull down screen.
| Protein Name | Gene | Source |
|---|---|---|
| Cell Surface CSPGs | ||
|
| ||
| Chondroitin sulfate proteoglycan 4 | CSPG4 | U2OS, C32, RH30 |
| Amyloid-like protein 2 | APLP2 | U2OS, PC3, Myla2059, C32 |
| Syndecan-1 | SDC1 | U2OS, PC3, C32, RH30 |
| CD44 | CD44 | U2OS, C32, Myla2059, RH30 |
| Integrin beta-1 | ITGB1 | U2OS, C32 |
| Syndecan-4 | SDC4 | U2OS, C32, Myla2059 |
| Glypican-1 | GPC1 | U2OS |
| Sushi repeat-containing protein | SRPX | U2OS, C32 |
| Neuropilin-1 | NRP1 | U2OS, PC3 |
| Sushi repeat-containing protein 2 | SRPX2 | U2OS |
| Syndecan 2 | SDC2 | C32 |
| Neuropilin-2 | NRP2 | C32 |
| Glypican-2 | GPC2 | C32 |
| Glypican-6 | GPC6 | C32 |
| Glypican-4 | GPC4 | C32 |
| Endorepellin | HSPG2 | C32 |
| Delta-sarcoglycan | SGCD | C32 |
| Agrin | AGRN | C32, Myla2059 |
| Syndecan-3 | SDC3 | C32 |
| HLA class II histocompatibility antigen gamma chain | CD74 | C32, Myla2059 |
| Laminin subunit alpha-4 | LAMA4 | C32 |
| Leukocyte surface antigen CD47 | CD47 | Myla2059 |
| Testican-1 | SPOCK1 | Myla2059 |
|
| ||
| Secreted CSPGs | ||
|
| ||
| Serglycin | SRGN | PC3, Myla2059 |
Each CSPG hit is listed at either cell surface or secreted. The hits are given by name and gene. The source of these hits is given in the right column.