Table 3.

Comparison of Urinary Pregnanediol Glucuronide (PDG), Estrone Conjugates (E1c), Follicle Stimulating Hormone (FSH), and Luteinizing Hormone (LH) Among Cancer Survivors, Same Age Controls and Late Reproductive Age Controls

	Cancer survivors (n=13)	Same age controls (n=11)	Late reproductive age controls (n=14)	p value Survivors vs. Same age	p value Survivors vs. Late Reproductive age	p value Same age vs. Late Reproductive age
PDG Total	40.0 (31.5-50.9)	47.1 (36.1-61.5)	28.2 (22.3-35.5)	0.37	0.04	<0.01
PDG Peak	3.78 (2.82-5.07)	4.47 (3.23-6.18)	2.57 (1.93-3.40)	0.45	0.06	0.01
PDG Luteal	24.6 (18.4-33.1)	28.3 (20.0-39.9)	19.7 (14.9-26.1)	0.55	0.27	0.11
PDG Follicular	12.9 (9.3-17.9)	16.2 (11.3-23.3)	6.8 (5.0-9.3)	0.35	<0.01	<0.01
E1c Total	1863 (1482-2344)	1109 (860-1430)	1314 (1054-1638)	0.01	0.03	0.32
E1c Peak	169 (128-222)	76 (56-104)	91 (69.8-118.4)	<0.01	<0.01	0.39
E1c Luteal	848 (610-1178)	570 (388-838)	682 (497-936)	0.13	0.34	0.47
E1c Follicular	908 (638-1291)	537 (363-793)	443 (316-621)	0.05	<0.01	0.46
FSH Total	839 (642-1096)	804 (598-1081)	841 (651-1087)	0.83	0.99	0.82
FSH Peak	93 (64-134)	64 (42-96)	79 (56-113)	0.18	0.54	0.42
FSH Follicular	475 (317-710)	428 (274-669)	357 (242-523)	0.73	0.31	0.54
FSH Luteal	286 (210-386)	305 (213-435)	387 (289-519)	0.78	0.15	0.30
LH Total	134 (99-181)	126 (90-175)	138 (104-184)	0.78	0.89	0.66
LH Peak	26 (17-39)	19 (12-31)	23 (15-35)	0.37	0.70	0.57
LH Follicular	67 (48-93)	63 (43-92)	56 (41-78)	0.83	0.47	0.64
LH Luteal	44 (29-67)	47 (29-77)	56 (38-83)	0.83	0.40	0.59

^*Data presented as geometric mean and 95% CI adjusted for cycle length and days missing