. Author manuscript; available in PMC: 2017 Dec 15.

Published in final edited form as: J Immunol. 2016 Nov 14;197(12):4848–4858. doi: 10.4049/jimmunol.1600763

Table II.

BCR sequencing summary

Sample	HCV status	Time point tested (estimated)	Sorted cells	Sorted cell number	Productive sequences Total	Productive sequences Unique	Clonality
HCV-8	Chronic HCV	5 years	Naive B cells^*	40 000	414 673	9 611	0.037
HCV-8	Chronic HCV	5 years	HCV E2- specific B cells^**	250	4 643	32	0.355
HCV-9	Chronic HCV	6 years	Naive B cells	40 000	996 999	11 927	0.029
HCV-9	Chronic HCV	6 years	HCV E2- specific B cells	220	10 814	62	0.089

Naive B cells are CD19+CD27-CD10-CD21hi

^**

HCV E2 specific B cells are class-switched memory B cells (CD19+CD27+IgM−)