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. Author manuscript; available in PMC: 2017 Dec 15.
Published in final edited form as: J Immunol. 2016 Nov 14;197(12):4626–4638. doi: 10.4049/jimmunol.1601488

Fig 7. Muller glial cell activation and induction of inflammatory and apoptotic mediators in the retina of D2 mice treated with AAV2.sFasL.

Fig 7

(A) Representative confocal microscopy images of paraffin embedded retinal sections taken from D2-Gp, D2-uninj. D2-AAV2-eGFP, and D2-AAV2-sFasL mice at 10 months of age and stained for GFAP (red) and DAPI (blue) (Scale bar, 100μm). Quantitative RT- PCR was performed on the neural retina isolated from D2-Gp, D2-uninj., D2-AAV2-eGFP, and D2-AAV2-sFasL mice at 10 months of age to quantitate mRNA levels of (B) GFAP, (C) TNFα, (D) pro-apoptotic mediators Fas, FADD, and BAX, and (E) anti-apoptotic mediators cFLIP, Bcl2, and cIAP2. N=5–6 per group. Error bar indicates SEM. *P<0.05, **<0.01, ***P<0.001, ****<0.0001.