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. Author manuscript; available in PMC: 2017 Dec 1.
Published in final edited form as: Mol Cancer Ther. 2016 Oct 7;15(12):2863–2874. doi: 10.1158/1535-7163.MCT-16-0515

Figure 3. Effect of treatment with fisetin, cabazitaxel and their combination on tumor growth and metastasis in mice implanted with 22Rν1 cells.

Figure 3

A. Line graph showing tumor volume growth determined by weekly measurements. Each value in the graph is the mean ± SE from six mice. ***, p ≤ 0.0005 was considered as significant. B. Line graph showing survival analysis. C. At the end of study, tumors were harvested from mice, subjected to IHC for proliferation (anti-ki67) and (anti-PCNA) and apoptosis (anti- BAX) and (anti-Bcl-2). Left, representative photomicrographs of Ki67, PCNA, BAX and Bcl-2-stained tumor section (40x). Right, quantitation of Ki67, PCNA, BAX and Bcl-2; ***, p ≤ 0.0001.