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. Author manuscript; available in PMC: 2017 Dec 1.
Published in final edited form as: Mol Cancer Res. 2016 Sep 16;14(12):1182–1194. doi: 10.1158/1541-7786.MCR-16-0111

Figure 6. Genetic deletion of AMPKα2 results in larger tumors in a BBN carcinogen-induced bladder tumor model.

Figure 6

A. Bladder weights of wild-type and AMPKα2-/- mice after 20 weeks of continuous BBN supplementation in drinking water (n=20/group). B. Representative images of p-AMPKα staining. C. Quantification of p-AMPKα staining in wild-type and AMPKα2-/- bladders. D. Representative images of tAMPKα staining. E. Quantification of tAMPKα staining in wild-type and AMPKα2-/- bladders. F. Representative images of KI67 staining. G. Quantification of KI67 staining in wild-type and AMPKα2-/- bladders. H. Representative images of p-S6 staining. I. Quantification of p-S6 staining in wild-type and AMPKα2-/- bladders. J. Representative images of p27 staining. K. Quantification of p27 staining in wild-type and AMPKα2-/- bladders. L. Representative images of SKP2 staining. M. Quantification of SKP2 staining in wild-type and AMPKα2-/- bladders. Statistical significance indicated as; *p<0.05