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. 2016 Nov 29;12:3051–3059. doi: 10.2147/NDT.S117337

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© 2016 Luo et al. This work is published and licensed by Dove Medical Press Limited

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CRPHF reduced depressive-like behaviors in diabetic rats.

Notes: (A) and (B) CRPHF increased the frequency of line crossing and rearing in the open field test; (C) and (D) CRPHF increased the total time and the number of entries in the open arms in the elevated plus-maze test; (E) CRPHF increased the locomotor activity of diabetic rats; (F) CRPHF decreased the immobility time of rats in the forced swimming test. ^#P<0.05, ^##P<0.01, and ^###P<0.0001 versus the N group and ^***P<0.0001 versus the D group (n=6 per group).

Abbreviations: CRPHF, combination of Radix Puerariae and hawthorn fruit; D, diabetic control; DC, diabetic-given-CRPHF; N, normal control; NC, normal-given-CRPHF.