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. 2016 Nov 29;12:3051–3059. doi: 10.2147/NDT.S117337

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© 2016 Luo et al. This work is published and licensed by Dove Medical Press Limited

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CRPHF increased the protein levels of p-ERK and BDNF in the brain of diabetic rats.

Notes: Top panels (A) and (B) are representative images of immunoblots of 42/44 kDa p-ERK and 28 kDa BDNF; lower panels (C) and (D) show the protein level of p-ERK and BDNF in the brain of rats. All data are shown as mean ± standard deviation; n=6 per group. ^###P<0.0001 versus the N group and ^**P<0.01 and ^***P<0.0001 versus the D group.

Abbreviations: BDNF, brain-derived neurotrophic factor; CRPHF, combination of Radix Puerariae and hawthorn fruit; D, diabetic control; DC, diabetic-given-CRPHF; N, normal control; NC, normal-given-CRPHF; p-ERK, phosphorylated extracellular signal-regulated protein kinase.