Table 1.
Classes of ncRNAs implicated in repair and genome stability. All abbreviations are defined in the text.
| Classes of ncRNAs | Ago Effector subfamily |
Size (bp) |
Localization | Functions |
|---|---|---|---|---|
| lncRNA | N/A | >200 | Nucleus | TGS, heterochromatin formation, genome organization and DSB repair |
| miRNA | Ago | 19–24 | Cytoplasm | PTGS (mRNA degradation, translational repression) |
| siRNA | Ago | 21–24 | Nucleus | TGS, heterochromatin formation, chromosome segregation |
| piRNA | PIWI | 23–31 | Nucleus Cytoplasm |
Transposon silencing (TGS and PTGS) |
| diRNA | Ago | 21–24 | Nucleus | DSB repair |