Figure 6.
Summary of phenotypes in Trp53bp2Δ3/Δ3 and Trp53bp2Δ3/+ embryos. Abnormalities detected by naked eye (visual inspection), microCT, and HREM in E13.5 and E14.5 ASPP2-deficient embryos. Frequency and the number of embryos evaluated for each phenotype are given. Wild-type littermate embryos were used as reference controls. In the case of BALB/c embryos, eye abnormalities were difficult to determine visually and were therefore quantified for a small number of embryos