Table 1.

Commonly Used Antiretrovirals with Typical Use in LMICs and High-Income Countries.

Drug Class	Drug Name	Abbreviation	LMIC Use	High-income Country Use
NRTIs	Lamivudine	3TC	First-line, second-line	First-line, second-line
	Emtricitabine	FTC	First-line, second-line	First-line, second-line
	Tenofovir	TDF	First-line, second-line	First-line, second-line
	Abacavir	ABC	Not commonly used (HLA testing required)	First-line, second-line
	Zidovudine	AZT	Alternative first-line, second-line	Salvage
NNRTIs	Efavirenz	EFV	First-line	Alternative first-line
	Rilpivirine	RPV	Not commonly used	Alternative first-line
	Etravirine	ETR	Not commonly used	Second-line, salvage
	Nevirapine	NVP	Alternative first-line	Not commonly used
PIs	Atazanavir	ATV	Second-line	Alternative first-line
	Darunavir	DRV	Alternative second-line, third-line	First-line, second-line, salvage
	Lopinavir	LPV	Second-line	Not commonly used
INSTIs	Elvitegravir	EVG	Not commonly used	First-line
	Raltegravir	RAL	Alternative second-line, third-line	First-line
	Dolutegravir	DTG	Alternative first-line	First-line, second-line, salvage
CCR5 Antagonist	Maraviroc	MVC	Not commonly used	Salvage

Abbreviations: NRTIs: nucleoside reverse transcriptase inhibitors; NNRTIs: non-nucleoside reverse transcriptase inhibitors; PIs: protease inhibitors; INSTIs: integrase strand transfer inhibitors; LMIC: low- and middle-income countries (Panel on Antiretroviral Guidelines for Adults and Adolescents, 2016; World Health Organization, 2015a).