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. 2016 Feb 25;75(12):2150–2156. doi: 10.1136/annrheumdis-2015-208640

Figure 2.

Figure 2

Homozygosity for the ankylosing spondylitis (AS)-risk allele at rs11209032 is associated with increased Th1-cell frequencies. (A) The % of interferon (IFN)-γ+ CD4+ T-cells in patients with AS of each genotype at rs11209032 (19 GG, 25 GA, 8 AA). (B) The % of interleukin (IL)-17A+ CD4+ T-cells in patients with AS of each genotype at rs11209032 (19 GG, 25 GA, 8 AA). (C) The % of IFN-γ+ CD4+ T-cells in patients with AS of each genotype at rs6677188 (33 TT, 17 TA, 2 AA). Patients ‘A/A’ at rs11209032 are highlighted by open circles. (D) The % of IL-17A+ CD4+ T-cells in patients with AS of each genotype at rs6677188 (33 TT, 17 TA, 2 AA). The percentage of cells is expressed as mean±SEM. Student's t test was used.