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. 2016 May 17;69(11):968–973. doi: 10.1136/jclinpath-2016-203641

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A predicted stem-loop sequence is present near the start of the vacA 5′ untranslated region (UTR). (A) The intergenic region between the 3′ end of the upstream gene cysS (diagonal hatched box) and the start of the vacA open reading frame (white box) is shown with the −35 and −10 consensus promoter sequence positions, the transcriptional start site (+1) and the 5′ UTR (thick line) indicated. (B) The predicted mRNA fold of a potential stem-loop sequence located at +4 to +30 in the vacA 5′ UTR, with a G/A polymorphism at position +28 shown.