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. 2016 Dec 5;6:38365. doi: 10.1038/srep38365

Table 2. The HRs/ORs value and concomitant variables of included studies.

Author Year Distant metastasis (OR/HR) lymph node metastasis (OR/HR) Survival analysis HR (95% CI) P Concomitant variables
Li J5 2008 9.930 (2.200–44.820) 1.714 (0.999–2.943) OS (M) 2.906 (1.810–4.668) <0.001 T classification, N classification.
Hu GH14 2009 4.280 (1.320–13.900) (M) / CSS (U) 8.300 (1.894–36.376) 0.005 ER, PR, HER2, p53 and tumor size.
Su P15 2010 / 1.094 (0.587–2.038) / / /  
Li C16 2011 3.875 (1.647–9.118) 3.188 (1.524–6.671) OS (M) 3.484 (1.505–8.062) <0.001 tumor size, lymphatic and venous invasion, lymph node status.
        DFS (M) 3.032 (1.388–6.622) 0.014  
Tokunaga E23 2014 2.39 (1.08–5.01) (M) 1.771 (0.861–3.642) DFS (M) 3.450 (1.690–6.840) 0.001 tumor size, nodal involvement, nuclear grade, lymphovascular invasion, ER, PR, HER2.
        OS (U)a 1.950 (1.173–3.241) 0.01  
Tan LS25 2015 2.604 (1.084–6.257) 3.900 (1.724–8.821) OS (U)a 3.140 (1.230–8.010) 0.017  
        DFS (U)a 2.540 (1.140–5.660) 0.023  
Meng F6 2011 / / OS (M) 5.573 (2.199–14.124) <0.001 FIGO stage, residual tumor, histological type.
        DFS (M) 3.982 (1.913–8.286) <0.001  
Li C17 2011 8.541 (2.561–37.461) (M) 9.581 (2.613–23.214) (M) / / / FIGO stage, residual tumor size.
Li C18 2011 / / OS (M) 19.380 (7.518–34.192) <0.001 age, lymph node metastasis, histopathological differentiation, serum CA-125 level, cytoreduction, FIGO stage, residual tumour size, chemotherapy resistance.
Li C22 2014 / / OS (M) 2.673 (1.445–4.867) 0.002 age, primary malignancies, extent of disease, ascites, size, time to diagnosis.
Dong R20 2014 / / OS (U)a 1.280 (1.004–1.631) 0.046  
        DFS (U)a 1.200 (0.989–1.456) 0.065  
Zhou B26 2015 / 10.588 (1.312–85.438) OS (M) 3.037 (1.067–8.670) 0.036 age, histological type, differentiation degree, lymph node metastasis, clinical stage.
Huang K7 2013 / 4.050 (1.565–10.481) OS (M) 4.021 (1.734–8.283) 0.027 age, tumor size, histological classification, clinical stage, pathological grade, lymph node metastasis.
Song EL24 2014 / / OS (U)a 1.790 (1.105–2.900) 0.018  
Long M19 2013 6.781 (0.388–118.631) 18.616 (1.110–312.323) / / /  
Song HT8 2010 / 3.929 (1.437–10.743) OS (M) 4.960 (1.774–13.869) 0.002 FIGO stage, lymphatic and venous invasion, histological type.
        DFS (M) 3.573 (1.499–8.518) 0.004  
Wang Y27 2016 / 2.500 (1.101–5.676) OS (M) 8.644 (4.255–17.556) <0.001 FIGO stage, residual tumor.
        DFS (M) 5.132 (2.943–8.949) <0.001  
Jin P28 2013 4.429 (1.373–14.283) 1.699 (1.145–4.230) DFS (U)a 2.710 (1.070–6.900) 0.036  

HR: hazard ratio; OR: odds ratios; OS: overall survival; CSS: cancer-specific survival; DFS: disease-free survival; M: multivariate analysis; U: univariate analysis;

aextracted from survival curve; ER: estrogen receptor; PR: progesterone receptor; HER2: human epidermal growth factor receptor-2; FIGO: International Federation of Gynecology and Obstetrics.