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. 2016 Dec 5;6:37637. doi: 10.1038/srep37637

Table 1. ED-iPSC Summary of Analysis Performed.

iPSC Line Fibroblast Sourcea Fibroblast Pathologya iPSC Karyotypeb iPSC Pluripotencyb iPSC Teratomab,c iPSC Multi-Lineage Diff.d,e iPSC RNA-Seqd iPSC ChIP-seqd
Details As reported As reported Tested for abnormalities ICC Tested PCR Tested Germ layer expression In vitro targeted differentiation HighSeq 2500 v3 Four-plexed HighSeq 2500 v3 Four-plexed
A2.1.1 Coriell Institue Apparently healthy Normal XY ICC - Oct4A, Nanog, SSEA-4; RT-PCR – Oct4, Sox2, Nanog, Rex1 Ectoderm + Endoderm + Mesoderm+ Pancreatic; Neuronal; Astrocyte; Smooth muscle; Cardiac muscle 30 to 50 million single-end 50 bp reads H3K27ac; H3K4me1
A2.2.2 Coriell Institue Apparently healthy Normal XY ICC - Oct4A, Nanog, SSEA-4; RT-PCR – Oct4, Sox2, Nanog, Rex1 Ectoderm + Endoderm + Mesoderm+ Pancreatic; Neuronal; Astrocyte; Smooth muscle; Cardiac muscle 30 to 50 million single-end 50 bp reads H3K27ac; H3K4me1
F3.5.2 Coriell Institue Apparently healthy Normal XY ICC - Oct4A, Nanog, SSEA-4; RT-PCR – Oct4, Sox2, Nanog, Rex1 Ectoderm + Endoderm + Mesoderm+ Pancreatic; Neuronal; Astrocyte; Smooth muscle; Cardiac muscle 30 to 50 million single-end 50 bp reads H3K27ac; H3K4me1
F3.6.1 Coriell Institue Apparently healthy Normal XY ICC - Oct4A, Nanog, SSEA-4; RT-PCR – Oct4, Sox2, Nanog, Rex1 Ectoderm + Endoderm + Mesoderm+ Pancreatic; Neuronal; Astrocyte; Smooth muscle; Cardiac muscle 30 to 50 million single-end 50 bp reads H3K27ac; H3K4me1
H3.1.1 Coriell Institue Apparently healthy Normal XY ICC - Oct4A, Nanog, SSEA-4; RT-PCR – Oct4, Sox2, Nanog, Rex1 Ectoderm + Endoderm + Mesoderm+ Pancreatic; Neuronal; Astrocyte; Smooth muscle; Cardiac muscle 30 to 50 million single-end 50 bp reads H3K27ac; H3K4me1
H3.3.1 Coriell Institue Apparently healthy Normal XY ICC - Oct4A, Nanog, SSEA-4; RT-PCR – Oct4, Sox2, Nanog, Rex1 Ectoderm + Endoderm + Mesoderm+ Pancreatic; Neuronal; Astrocyte; Smooth muscle; Cardiac muscle 30 to 50 million single-end 50 bp reads H3K27ac; H3K4me1
H3.5.2 Coriell Institue Apparently healthy Normal XY ICC - Oct4A, Nanog, SSEA-4; RT-PCR – Oct4, Sox2, Nanog, Rex1 Ectoderm + Endoderm + Mesoderm+ Pancreatic; Neuronal; Astrocyte; Smooth muscle; Cardiac muscle 30 to 50 million single-end 50 bp reads H3K27ac; H3K4me1

aInformation available from the Coriell Institute.

bAnalysis described in Chang et al. (ref. 13).

cHistology included in Chang et al.

dCurrent study.

eSee also Table 2 in current study.