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. 2016 Nov 25;13:106–115. doi: 10.1016/j.nicl.2016.11.024

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© 2016 The Authors

This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

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Fig. 5 — Relationship between CSF proteins and FA in the merged younger-older fornix template. Regression of FA in the merged younger-older template against CSF Aβ₄₂ (A), and t-tau/Aβ₄₂ ratio (B) when controlling for the effects of age and sex. Significant relationships show that lower FA (worse white matter microstructure) in the fornix is associated with worse AD-related pathology markers. R² linear values are for the linear best fit (solid line), and dashed lines indicate the 95% confidence interval for the mean response.