Table 4.
Correlation of the expression levels of asthma genes with asthma and asthma severity in BAL
| Gene | Controls* (n=28) |
Mild/moderate* (n=38) |
Severe* (n=28) |
Cases* (n=66) |
P value
|
||
|---|---|---|---|---|---|---|---|
| Controls vs. Cases | Controls vs. Severe | Mild/moderate vs. Severe | |||||
| GSDMB | 7.64 (0.54) | 7.24 (0.48) | 7.7 (0.68) | 7.44 (0.61) | 0.75 | 0.14 | 0.0034 |
| IL18R1 | 2.76 (1) | 3.03 (0.87) | 3.81 (1.33) | 3.36 (1.15) | 0.02 | 0.0038 | 0.02 |
| IL13 | 2.18 (0.9) | 2.44 (1.23) | 2.31 (0.99) | 2.38 (1.13) | 0.03 | 0.04 | 0.68 |
| SMAD3 | 5.34 (0.82) | 4.99 (0.7) | 5.51 (1.14) | 5.21 (0.94) | 0.52 | 0.08 | 0.02 |
| IL6R | 7.87 (0.4) | 7.99 (0.37) | 8.23 (0.37) | 8.09 (0.38) | 0.04 | 0.0088 | 0.05 |
| USP38 | 5.97 (0.36) | 6.19 (0.33) | 6.02 (0.24) | 6.12 (0.31) | 0.58 | 0.28 | 0.0078 |
| AGER | 8.73 (0.48) | 8.35 (0.34) | 8.51 (0.46) | 8.42 (0.4) | 0.03 | 0.29 | 0.11 |
| DEXI | 9.57 (0.42) | 9.58 (0.32) | 9.82 (0.43) | 9.68 (0.39) | 0.16 | 0.05 | 0.03 |
*
Log2 transformed expression values (standard deviation) were reported.
#
Only entries with P values<0.05 were included.