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. 2015 May 22;51:10–21. doi: 10.1540/jsmr.51.10

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©2015 The Japan Society of Smooth Muscle Research

This is an open-access article distributed under the terms of the Creative Commons Attribution Non-Commercial No Derivatives (by-nc-nd) License.

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Fig. 1. — Effects of okadaic acid on bovine ciliary muscle strips. (a) A representative isometric tension recording showed that 2 µmol/l CCh induced a reversible contraction with a transient peak followed by a plateau phase in the BCM. After removal of CCh, it returned to the resting level. (b) Addition of 10 µmol/l okadaic acid to a relaxed BCM preparation produced a slow tension development. It slowly reverted to the resting level when okadaic acid was removed. (c) Addition of 1 µmol/l okadaic acid did not cause any change (98.1 ± 1.2%, n = 8, P = 0.16) in pre-contracted BCM with 2 µmol/l CCh.