Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2015 May 22;51:10–21. doi: 10.1540/jsmr.51.10

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

©2015 The Japan Society of Smooth Muscle Research

This is an open-access article distributed under the terms of the Creative Commons Attribution Non-Commercial No Derivatives (by-nc-nd) License.

PMC Copyright notice

Fig. 3. — Effects of fostriecin and rubratoxin A on bovine ciliary muscle strips. Fostriecin and rubratoxin A were added to BCM strips pre-contracted by CCh or ionomycin. (a) Following CCh-induced contraction, 3 µmol/l fostriecin did not cause any change (97.7 ± 3.4%, n = 6, P = 0.53). (b) With ionomycin-induced contraction, 3 µmol/l fostriecin inhibited contraction completely (2.0 ± 1.6%, n = 6, P < 0.01). (c) Rubratoxin A inhibited CCh-induced contraction at 10 µmol/l (1.7 ± 2.2%, n = 6, P < 0.01). (d) It also inhibited ionomycin-induced contraction. Three µmol/l rubratoxin A decreased ionomycin-induced tension to 63.2 ± 6.8% (n = 6, P < 0.01), and 10 µmol/l relaxed it completely (1.5 ± 1.7%, n = 6, P < 0.01).