Table 4.
Control | Anh.-like | |||||
---|---|---|---|---|---|---|
Per1 | Per2 | Bmal1 | Per1 | Per2 | Bmal1 | |
Pineal gland | ||||||
Peak | 18 | - | 2 | 14 | - | 22 |
Nadir | 10 | - | 14 | 6 | - | 10 |
Suprachisamatic nucleus | ||||||
Peak | 6 | 10 | 14 | 6 | 6 | 18 |
Nadir | 18 | 18 | 6 | 18 | 2 | 6 |
Hippocampus* | ||||||
Peak | 22 | - | - | 18 | - | - |
Nadir | 14 | - | - | 10 | - | - |
Liver | ||||||
Peak | 10 | 14 | 22 | 10 | 14 | 22 |
Nadir | 2 | 2 | 10 | 2 | 2 | 10 |
* = (CA1, CA3, and DG)
Peak and nadir of the control and anhedonic-like (anh.-like) rats for Per1, Per2, and Bmal1 clock genes in the pineal gland, suprachiasmatic nucleus, hippocampus, and liver. Peak and nadir are presented as zeitgeber time (ZT), where ZT 0 is defined as a time point when light in facilities is on.
– = no diurnal rhythm measured by two-way ANOVA.