Fig. 1.

Measurement of metabolic tumor volume (MTV) and mean maximum standardized uptake value (SUV_mean). (A) We made the volume of interest (VOI) to sufficiently surround the fluorodeoxyglucose (FDG) uptake area (green line). The volume of over or equal to the FDG value X was automatically measured (red line). (B) SUV_mean was defined as the average of the SUV in the outline of the tumor at the level of the greatest tumor dimensions at the pulmonary window of a positron emission tomography – computed tomography (PET/CT) axial image.