Table 1. ECM-associated proteins.
| # | AC | ID | Description | ECM/NI Ratio |
ECM/d3 pi Ratio |
||
|---|---|---|---|---|---|---|---|
| TMT6 #1 | TMT6 #2 | TMT6 #1 | TMT6 #2 | ||||
| 1 | P05366 | SAA1_MOUSE | Serum amyloid A-1 protein | 4.16 | 3.52 | 4.66 | 4.43 |
| 2 | P05367 | SAA2_MOUSE | Amyloid protein A | 3.81 | — | 4.71 | — |
| 3 | P01942 | HBA_MOUSE | Hemoglobin subunit alpha | 3.56 | 3.51 | 4.16 | 3.14 |
| 4 | P02089 | HBB2_MOUSE | Hemoglobin subunit beta-2 | 3.27 | 3.56 | 3.70 | 3.19 |
| 5 | P00920 | CAH2_MOUSE | Carbonic anhydrase 2 (CA-II) | 3.39 | 3.31 | 4.20 | 3.20 |
| 6 | P01872 | IGHM_MOUSE | Ig mu chain C region | 3.25 | — | 3.56 | 2.50 |
| 7 | Q61171 | PRDX2_MOUSE | Peroxiredoxin-2 (TSA) | 3.10 | 3.25 | 3.29 | 3.21 |
| 8 | P02088 | HBB1_MOUSE | Hemoglobin subunit beta-1 | 2.99 | 3.25 | 3.32 | 2.83 |
| 9 | P08113 | ENPL_MOUSE | Endoplasmin (GRP-94) (ERp99) | 3.02 | — | — | — |
| 10 | P04919 | B3AT_MOUSE | Band 3 anion transport protein, Isoform Kidney | 2.37 | 3.25 | 2.83 | 2.73 |
| 11 | Q9QWK4 | CD5L_MOUSE | CD5 antigen-like | 2.75 | — | 3.22 | — |
| 12 | P06800 | PTPRC_MOUSE | Receptor-type tyrosine-protein phosphatase C, Isoform 3 | 2.32 | 3.27 | 2.85 | 3.33 |
| 13 | P09103 | PDIA1_MOUSE | Protein disulfide-isomerase (PDI) (ER protein 59) | 2.75 | — | — | — |
| 14 | P01837 | IGKC_MOUSE | Ig kappa chain C region | 2.64 | — | 3.41 | — |
| 15 | P13634 | CAH1_MOUSE | Carbonic anhydrase 1 (CA-I) | 2.86 | 2.40 | 3.67 | 2.69 |
| 16 | P04918 | SAA3_MOUSE | Serum amyloid A-3 protein | 2.52 | — | 2.67 | — |
| 17 | P01831 | THY1_MOUSE | Thy-1 membrane glycoprotein | — | 2.51 | — | — |
| 18 | P11835 | ITB2_MOUSE | Integrin beta-2 | 2.17 | 2.70 | 2.46 | 2.70 |
| 19 | Q02013 | AQP1_MOUSE | Aquaporin-1 (AQP-1) (DER2) | 2.28 | 2.37 | 3.38 | 2.30 |
| 20 | P27773 | PDIA3_MOUSE | Protein disulfide-isomerase A3 (p58) (ERp57) (ERp60) | 2.28 | — | 2.42 | — |
| 21 | P01897 | HA1L_MOUSE | H-2 class I histocompatibility antigen, L-D alpha chain | — | 2.28 | — | — |
| 22 | P24063 | ITAL_MOUSE | Integrin alpha-L (LFA-1A) (Ly-15) | — | 2.18 | 2.36 | 2.23 |
| 23 | P05555 | ITAM_MOUSE | Integrin alpha-M, Isoform 2 | — | 2.14 | — | 2.28 |
| 24 | Q02105 | C1QC_MOUSE | Complement C1q subcomponent subunit C | 2.13 | — | 2.25 | — |
| 25 | P12246 | SAMP_MOUSE | Serum amyloid P-component (SAP) | 2.12 | — | — | — |
| 26 | P20491 | FCERG_MOUSE | High affinity Ig epsilon receptor subunit gamma | 2.12 | — | 3.15 | — |
| 27 | P60766 | CDC42_MOUSE | Cell division control protein 42 homolog | — | 2.12 | 2.19 | 2.17 |
| 28 | P08032 | SPTA1_MOUSE | Spectrin alpha chain, erythrocytic 1 | — | 2.10 | — | 2.06 |
| 29 | P03987 | IGHG3_MOUSE | Ig gamma-3 chain C region, Isoform 2 | 2.09 | — | 2.56 | — |
| 30 | Q61735 | CD47_MOUSE | Leukocyte surface antigen CD47 (IAP) | 2.08 | — | 2.76 | — |
| 31 | P54116 | STOM_MOUSE | Erythrocyte band 7 integral membrane protein | 2.08 | — | 2.30 | — |
| 32 | P17182 | ENOA_MOUSE | Alpha-enolase (NNE) | — | — | — | 2.51 |
| 33 | P07356 | ANXA2_MOUSE | Annexin A2 (PAP-IV) | — | — | 2.37 | 2.32 |
| 34 | P62880 | GBB2_MOUSE | Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2 | — | — | 2.28 | — |
| 35 | Q62469 | ITA2_MOUSE | Integrin alpha-2 (GPIa) | — | — | — | 2.27 |
| 36 | P01630 | KV2A6_MOUSE | Ig kappa chain V-II region 7S34.1 | — | — | 2.23 | — |
| 37 | P26041 | MOES_MOUSE | Moesin | — | — | 2.30 | 2.15 |
| 38 | P18572 | BASI_MOUSE | Basigin, Isoform 2 | — | — | 2.19 | — |
| 39 | P06151 | LDHA_MOUSE | L-lactate dehydrogenase A chain (LDH-A) (LDH-M) | — | — | — | 2.19 |
| 40 | P01631 | KV2A7_MOUSE | Ig kappa chain V-II region 26-10 | — | — | 2.13 | — |
| 41 | P15702 | LEUK_MOUSE | Leukosialin (Ly-48) | — | — | — | 2.12 |
| 42 | P01592 | IGJ_MOUSE | Immunoglobulin J chain | — | — | 2.07 | — |
| 43 | Q60963 | PAFA_MOUSE | Platelet-activating factor acetylhydrolase (PAF acetylhydrolase) | Only ID | |||
| 44 | P68254 | 1433T_MOUSE | 14-3-3 protein theta | Only ID | |||
| 45 | Q61646 | HPT_MOUSE | Haptoglobin beta | Only ID | |||
| 46 | P21981 | TGM2_MOUSE | Protein-glutamine gamma-glutamyltransferase 2 | Only ID | |||
| 47 | P17156 | HSP72_MOUSE | Heat shock-related 70 kDa protein 2 | Only ID | |||
| 48 | P84244 | H33_MOUSE | Histone H3.3 | Only ID | |||
| 49 | P31725 | S10A9_MOUSE | Protein S100-A9 (MRP-14) (p14) | Only ID | |||
| 51 | P27661 | H2AX_MOUSE | Histone H2AX (H2a/x) | Only ID | |||
| 52 | P01670 | KV3AI_MOUSE | Ig kappa chain V-III region PC 6684 | Only ID | |||
| 53 | P14426 | HA13_MOUSE | H-2 class I histocompatibility antigen, D-K alpha chain (H-2D(K) | Only ID | |||
| 54 | P0CW03 | LY6C2_MOUSE | Lymphocyte antigen 6C2 (Ly-6C2) | Only ID | |||
| 55 | Q8BFZ3 | ACTBL_MOUSE | Beta-actin-like protein 2 | Only ID | |||
| 56 | P01749 | HVM05_MOUSE | Ig heavy chain V region 3 | Only ID | |||
| 57 | P01646 | KV5AD_MOUSE | Ig kappa chain V-V region HP 123E6 | Only ID | |||
| 58 | P27005 | S10A8_MOUSE | Protein S100-A8 (MRP-8) | Only ID | |||
| 59 | P62806 | H4_MOUSE | Histone H4 | Only ID | |||
| 60 | P11672 | NGAL_MOUSE | Neutrophil gelatinase-associated lipocalin (NGAL) | Only ID | |||
| 61 | Q8CGP1 | H2B1K_MOUSE | Histone H2B type 1-K | Only ID | |||
| 62 | P50446 | K2C6A_MOUSE | Keratin, type II cytoskeletal 6 A (CK-6A) | Only ID | |||
| 63 | O08677 | KNG1_MOUSE | Kininogen-1 light chain, Isoform 3 | Only ID | |||
List of proteins significantly over-expressed in ECM either compared to d3 pi or to NI (TMT6 experiments #1 and #2) and proteins uniquely identified (Only ID) in the ECM sample (TMT0 experiment). —: non differential expression.