Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2016 Jul 15;44(21):10423–10436. doi: 10.1093/nar/gkw637

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2016. Published by Oxford University Press on behalf of Nucleic Acids Research.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.

PMC Copyright notice

Figure 4. — RAM stabilises RNMT in molecular dynamic simulations. (A) Heatmaps displaying backbone RMSD of the hinge (residues 395–416) versus RMSD of helix A (residues 341–345), calculated from 60ns high temperature MD trajectories of RNMT, RNMT–RAM and RNMTΔ416–456. The colour scale represents the number of snapshots in each ‘bin’. (B) Representative snapshots corresponding to the most sampled configuration in panel A. Helix A is shown in blue, hinge in green and lobe in orange. High-transparency image of helix A in the background represents the position in RNMT–RAM crystal structure.

HHS Vulnerability Disclosure