Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2016 Sep 1;44(21):10230–10247. doi: 10.1093/nar/gkw760

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2016. Published by Oxford University Press on behalf of Nucleic Acids Research.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.

PMC Copyright notice

Figure 4. — Genome-wide analysis of DNA replication origin distributions. Enrichment peaks of immunoprecipitated nascent DNA (origin peaks) were called by SICER, excluding the input DNA library. Only peaks present in both libraries IP-A and IP-B (i.e. the intersect) are subsequently analysed. (A) Distribution plot of origin peak counts for each individual human chromosome. Individual chromosome lengths are indicated by asterisks. (B) Distributions of origin peak widths for each human chromosome. Box and whisker plots are shown without individual outliers, whiskers represent 1.5 times the interquartile range above the upper quartile and below the lower quartile, and the overall genomic median is indicated. (C and D) Origin spacing. Inter-origin distances were calculated in 5 kb intervals for the distributions of activated replication origins (green) and control sites (dashed grey) that were randomised either (C) within each chromosome, or (D) within DNA replication timing windows (46).