Figure 1.

Amino acid sequence for the N-terminal regions of TDG^82-308 and TDG^111-308 and the initial residues of the bacterial homologue MUG (E. coli). Putative sites for post-translational modification are indicated for TDG^82-308, including acetylation (A) and phosphorylation (P). Also shown is the PIP degron and an α-helix that has not been observed in previous structures of E·S complexes. Shown in red for TDG^111-308 are the six non-native residues that remain after removal of the poly-His tag. All residues of TDG^82-308 are native to TDG.