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. 2016 Oct 13;44(21):10480–10490. doi: 10.1093/nar/gkw931

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© The Author(s) 2016. Published by Oxford University Press on behalf of Nucleic Acids Research.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com

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Figure 6. — Structural comparison of non-specific and specific endonucleases that contain ββα-metal motifs. (A) Overall conformations of three non-specific endonucleases: CPS-6 (this study, PDB entry: 5GKP), Vvn (PDB entry: 1OUP) and ColE7 (PDB entry: 2IVH). (B) Overall conformations of three sequence- or structure-specific endonucleases: I-PpoI (PDB entry: 1A74), Hpy99I (PDB entry: 3GOX) and T4 endo VII (PDB entry: 2QNC). The ββα-metal motifs are displayed in cyan. The endonuclease cleavage sites are marked by scissors.