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. 2016 Oct 7;17(11):1117–1125. doi: 10.1080/15384047.2016.1235654

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Figure 1. — HPLC-purified CAP showed inhibitory effect on cancer cell viability. (A) Chemical formula for CAP. (B) HPLC analysis of CAP-containing products. Upper panel: capsaicinoids obtained by supercritical carbon dioxide extraction. Lower panel: Highly purified CAP product obtained by semi-preparative HPLC. (C-E) Cell viability of CAP-treated cancer cells. Cells were treated for 48 h with 0–16 μg/ml of CAP. Asterisk: Significant difference (*: p < 0.05, **: p < 0.01) compared to DMSO treatment.