Figure 2.
Cytokine concentrations in plasma (A) and lung homogenates (B) in the premixed setting. Saline, low titer hu-IgG, high titer hu-IgG, or anti-PcrV rab-IgG was premixed with a lethal dose (1.5 × 106 CFU/mouse) of Pseudomonas aeruginosa PA103 just before tracheal instillation. Blood from the surviving mice and the lungs from all mice were collected 24 h post-instillation. Data are presented as median, first (boxes), and second quartiles (bars) with each value indicated by circles; *, p < 0.05 compared with the saline-premixed group; ‡, p < 0.05 compared with the no bacteria control group.