Skip to main content
. 2016 Jul 25;12(11):2881–2901. doi: 10.1080/21645515.2016.1210729

Table 2.

Overview of vector-based influenza vaccines.

Vector Model Antigen Modification Subtype Reference
           
Alphavirus graphic file with name khvi-12-11-1210729-i001.gif HA n/a H1N1 100,103,105
  NP CD8 epitope n/a 104
 
 
HA/NP
n/a
H1N1
98
           
  graphic file with name khvi-12-11-1210729-i003.gif HA n/a H1N1, H3N2 107-111
  NP n/a H3N2 111
 
 
HA/NP
n/a
H3N2
107
           
 
Inline graphic
HA
n/a
H5N1
106
Herpesvirus
Inline graphic
HA
n/a
H1N1, H3N2, H3N8
130,131,133
           
  graphic file with name khvi-12-11-1210729-i003.gif HA n/a H1N1 129,134
 
 
HA/NA
n/a
H1N1
128
           
  graphic file with name khvi-12-11-1210729-i004.gif HA n/a H5N1, H5N2, H7N1 115,117-126
  NA n/a H5N1 120
 
 
HA/NA
n/a
H5N1
120
           
 
Inline graphic
HA
n/a
H5, H5N1
114
           
 
Inline graphic
HA
n/a
H3N8
131
           
 
Inline graphic
HA
n/a
H3N8
132
VSV graphic file with name khvi-12-11-1210729-i001.gif HA n/a H1N1, H5N1 136,139,143,145
  HA Chimeric cH5/1, cH9/1 140
  NP n/a H1N1 139
  HA/NP n/a H1N1 139
 
 
HA/NA
n/a
H1N1, H5N1
140
           
 
Inline graphic
HA
n/a
H5N1, H7N1
142
           
  graphic file with name khvi-12-11-1210729-i012.gif HA n/a H5N1 144
NDV graphic file with name khvi-12-11-1210729-i001.gif HA n/a H1N1, H5N1 147,158,159,167
 
 
HA
Soluble
H5N1
158
           
  graphic file with name khvi-12-11-1210729-i004.gif HA n/a H5N1, H5N2, H6, H7, H7N2, H7N9, H9N2 149,150,152,153,155-166
  HA Soluble H5N1 158
  HA Ectodomain H5N1 151
 
 
HA/NA
n/a
H5N1
155
           
 
Inline graphic
HA
n/a
H6
165
           
 
Inline graphic
HA
n/a
H5N1, H5N8
149,154
           
 
Inline graphic
HA
n/a
H5N1
168,169
Baculo
Inline graphic
HA
n/a
H1N1, H5N1, H6N8, H7N9, H9N2
171-178
PIV-5 graphic file with name khvi-12-11-1210729-i001.gif HA n/a H3N2, H5N1, H7N9 180-182
 
 
NP
n/a
H5N1
182
           
  graphic file with name khvi-12-11-1210729-i010.gif HA n/a H7N9 181
 
 
HA/NP
n/a
H7N9
181
           
  graphic file with name khvi-12-11-1210729-i007.gif HA n/a H3N2 179