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. 2016 Jul 25;12(11):2881–2901. doi: 10.1080/21645515.2016.1210729

Table 3.

Overview of adenovirus-based influenza vaccines.

Vector Model Antigen Modification Subtype Reference
           
Adenoviruses graphic file with name khvi-12-11-1210729-i001.gif HA n/a H3N2, H5N1, H7N7, H9N2 191,193-195,199,201-204,206
  HA Soluble head H1N1 198
  HA Glycan shielded H5N1 207
  NP n/a H1N1, H5N1 192,208,209,214
  M2 Consensus n/a 180
  HA/NP n/a H5N1, H7N7, H9N2 206
  HA/NA n/a H1N1 211
  NP/M2 n/a H1N1 216
  NP/M2 Consensus H1N1 210
  HA/NA/M1 n/a H1N1, H5N! 213
 
 
NP/M1/M2
miRNAs
H1N1
211
           
  graphic file with name khvi-12-11-1210729-i002.gif HA n/a H5N1 203,215
  NP n/a H5N1 215
  M2 n/a H5N1 215
  HA/NA Consensus H1N1 212
  NP/M2 n/a H1N1, H5N1 215,216
 
 
HA/NP/M2
n/a
H5N1
215
           
  graphic file with name khvi-12-11-1210729-i003.gif HA n/a H1N1, H3N2 196,200
  NP n/a H3N2 196
 
 
HA/NP
n/a
H3N2
196
           
 
Inline graphic
HA
n/a
H5N1, H7N3
202,205
           
  graphic file with name khvi-12-11-1210729-i013.gif HA n/a H1N1, H5N1 187,188,190
 
 
NP/M1
n/a
H3N2
189
AAV graphic file with name khvi-12-11-1210729-i001.gif HA n/a H1N1 222
  HA Broadly neutralizing ab n/a 223,224
  NP n/a H1N1 222
  M1 n/a H1N1 222
 
 
HA/NP/M1
n/a
H1N1
222
           
  graphic file with name khvi-12-11-1210729-i002.gif HA Broadly neutralizing ab n/a 224