Table 3.
Variations in AD episode characteristics per protocol adherence
| Protocoled (n = 410 unless otherwise noted) | Protocol deviations (n = 35 unless otherwise noted) | All AD events | |
|---|---|---|---|
| Mean (SD) max SBP | 200.0 mmHg (24.2), n = 409 | 205.3 mmHg (18.1) | 200.4 mmHg (27.6), n = 444 |
| Mean (SD) max DBP | 109.1 mmHg (19.5), n = 409 | 109.4 mmHg (15.4) | 109.1 mmHg (19.1), n = 444 |
| Mean (SD) SBP drop from initial | 76.3 mmHg (36.6) | 60.6 mmHg (41.0) | 75.1 mmHg (37.2) |
| Rebound AD episodes | 12.4% | 31.4% | 14.0% |
| Percent attaining target BP | 97.6% | 57.1% | 94.4% |
| Mean (SD) episode duration | 63.1 min (76.0) n = 408 | 130.6 min (112.9) | 68.3 min (81.3), n = 439 |
| Relative hypotension percentage | 2.9% | 5.7% | 3.3% |
| Adverse events | 5.4% | 2.9% | 5.2% |