Fig. S3.

Increased rate of neuroblast production and neuronal differentiation is evident 9 mo after VEGF deinduction. (A) VEGF was induced for 1 mo (at the age of 2 mo) and then deinduced for an additional 9 mo. CldU (100 mg/kg, three i.p. injections) was administered 1 mo before euthanasia. (B) Laminin staining for BVs and quantification of vessel density in the DG. (C) DCX staining for neuroblasts and quantification. (D) Cells double-positive for CldU and the mature neuronal marker NeuN highlighting newborn neurons. (Scale bar: B–D, 100 μm.)