Fig. S8.

Vascular rejuvenation increases the production rate of neural progenitors (IPCs). The same mice used for visualizing and enumerating RGLs and their proliferation status (Fig. 5) were also used for visualizing total numbers of IPCs and IdU⁺ IPCs per volume unit. (A) Representative image of IPCs (identified as non-RGL/nestin⁺ cells, arrow) and symmetrically dividing IPCs (non-RGL nestin⁺/IdU⁺ cells, arrowhead). (Scale bar, 20 μm.) (B) Total IPCs number per volume unit. (C) Numbers of dividing IPCs per volume unit. (D) Fraction of proliferating IPCs from total IPCs. NS, not significant.