Fig. 5.

A disease phenotype in Ae. aegypti infected with recombinant SIN viruses expressing flavivirus capsid proteins. Shown are survival curves for mosquitoes infected with recombinant SIN viruses expressing flavivirus capsid proteins (red triangles). Significance was determined by comparing curves with the survival of mosquitoes infected with recombinant SINV containing a nontranslatable YFC (black circles; replicated for each panel from Fig. 3A) using the Mantel–Cox log-rank test. Survival curves represent cohorts of ≥40 adult female mosquitoes injected with 500 pfu of virus.