Table 1.
Baseline Characteristics of the Analyzed Participants, Overall and by Sampling Group
| Parameter | NLST Cohort (n = 53 452)* |
Analysis Population (n = 1442) |
Sampling Group | P Value† | ||
|---|---|---|---|---|---|---|
| CHD Deaths (n = 171) |
Deaths not from CHD (n = 295) |
Control Participants (n = 976) |
||||
| Mean age (y)‡ | 61 ± 5 | 62 ± 5 | 63 ± 5 | 63 ± 5 | 61 ± 5 | <.001 |
| Men | 31 530 (59) | 846 (59) | 115 (67) | 199 (67) | 532 (55) | <.001 |
| Race | .099 | |||||
| White | 48 549 (91) | 1331 (92) | 157 (92) | 263 (89) | 911 (93) | … |
| Black | 2376 (4) | 90 (6) | 10 (6) | 28 (9) | 52 (5) | … |
| Other | 2527 (5) | 21 (1) | 4 (2) | 4 (1) | 13 (1) | … |
| Education level | <.001 | |||||
| <12th grade | 3249 (6) | 104 (7) | 18 (11) | 30 (10) | 56 (6) | … |
| High school graduate or general educational development test |
12 712 (24) | 336 (23) | 33 (19) | 87 (29) | 216 (22) | … |
| Training after high school | 7434 (14) | 162 (11) | 23 (13) | 23 (8) | 116 (12) | … |
| Associate degree or some college |
12 277 (23) | 314 (22) | 41 (24) | 68 (23) | 205 (21) | … |
| Bachelor degree | 8946 (17) | 253 (18) | 25 (15) | 37 (13) | 191 (20) | … |
| Graduate school | 7600 (14) | 218 (15) | 25 (15) | 33 (11) | 160 (16) | … |
| Unknown/Other | 1234 (2) | 55 (4) | 6 (4) | 17 (6) | 32 (3) | … |
| Married | 35 589 (67) | 887 (62) | 101 (59) | 158 (54) | 628 (64) | .003 |
| Diabetes§ | 5174 (10) | 138 (10) | 32 (19) | 39 (13) | 67 (7) | <.001 |
| Hypertension‖ | 18 930 (35) | 508 (35) | 82 (48) | 111 (38) | 315 (32) | <.001 |
| Current smoker | 25 760 (48) | 773 (54) | 109 (64) | 190 (64) | 474 (49) | <.001 |
Note.—Data are number of participants and data in parentheses are percentages unless otherwise noted. Baseline characteristics of the entire NLST cohort are added for reference.
*
Number of participants less than that originally reported in the primary NLST manuscript because of two duplicate registrations discovered after publication.
†
P values correspond to comparisons of the distribution of each variable among the three sampling groups.
‡
Data are ± standard deviation.
§
Self-reported diagnosis of diabetes.
‖
Self-reported diagnosis of hypertension.