Table 1. . Comparison of demographics on and at end of hypoglycemic treatment.
| Parameter | On treatment | Treatment withdrawn | Difference (95% CI) | p-value |
|---|---|---|---|---|
| Comorbidities, mean (SD) |
4.1 (0.9) |
6.8 (1.6) |
2.7 (1.3–3.9) |
0.002 |
| Patients with dementia |
None |
4 (50%) |
– |
|
| Medications, mean (SD) |
6.4 (1.9) |
10.1 (2.2) |
3.7 (1.4–6.1) |
0.01 |
| bodyweight (kg), mean (SD) |
88 (22.4) |
75.4 (21.2) |
12.6 (5.9–19.3) |
0.003 |
| Mean (SD) ALT |
16.8 (4.3) |
18.4 (3.3) |
1.6 (2.4–5.7) |
0.4 |
| Mean (SD) eGFR |
46.9 (10.3) |
45.1 (10.8) |
1.8 (9.5–13.0) |
0.7 |
| Mean (SD) HbA1c | 6.2% (0.8) | 6.5% (0.7) | 0.3% (-1.1–0.5) | 0.4 |
The stable liver and kidney functions suggest that successful withdrawal of hypoglycemic medications was not due to deteriorating organ function.
ALT: Alanine transaminase; eGFR: Estimated glomerular filtration rate SD: Standard deviation.
Data taken from [50].