Table 2. . Royal College of Obstetrics and Gynecologists Recommendation.

All pregnant women	400 μg/day preconception until 12th week of pregnancy
High-risk pregnant women†	5 mg/day

^†High-risk women:

– History of neural tube defect in previous pregnancy

– History of neural tube defect in pregnant woman or in her partner

– Using certain epilepsy medications

– Diabetes or celiac disease

– BMI 30 or more

– Sickle cell anemia or thalassemia

Data taken from [15,16].