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. 2016 Jul 15;2(3):FSO135. doi: 10.4155/fsoa-2016-0030

Figure 6. . Pharmacokinetics and cellular uptake of tamoxifen-loaded nanostructured lipid carriers.

Figure 6. 

(A) Plasma concentration–time profiles of tamoxifen suspension and tamoxifen-loaded NLCs after single oral administration of 10 mg/kg to rats. (B) Flow-cytometric analysis for cell uptake studies. (a) Histogram of untreated control cells, and (b) histogram of cells after 3 h incubation with coumarin-6-labeled tamoxifen-loaded NLCs.

FL1-H: Fluorescence intensity histogram; NLC: Nanostructured lipid carrier; susp: Suspension; Tmx: Tamoxifen.

Reproduced with permission from [46] © Elsevier (2013).