Skip to main content
. 2016 Jul 15;2(3):FSO135. doi: 10.4155/fsoa-2016-0030

Figure 7. . Transport of saquinavir-loaded nanostructured lipid carriers across the intestinal barrier.

Figure 7. 

(A) The transport mechanisms used by the different nanostructured lipid carriers formulations. (B) Permeability (Papp) values for free saquinavir and the saquinavir-loaded nanostructured lipid carriers after 2 h of incubation with 100-μM verapamil, a P-gp inhibitor. Formulations with no inhibition were considered as controls (n = 3).

** p < 0.01; *** p < 0.001.

–: Absence of verapamil; +: Under verapamil inhibition.

NLC: Nanostructured lipid carrier; ns: No significance; SQV: Saquinavir.

Reproduced with permission from [34] © Elsevier (2013).