Figure 1. . Structure of the ABO gene locus and nucleotide sequences of A, B and O alleles.

Diagram of exon organization of the protein coding sequences (under shaded).

Reprinted with permission from the Tokushima Medical Association [11].

^†Entirely different deduced a.a sequence in O alleles due to frame-shifting caused by single base pair deletion.

a.a.: Amino acid; bp: Base pair; nt.: Nucleotide position.