Table 1. . Mean bodyweight gain (%) and relative organ weight (%) following intravenous administration of vehicle, 100 and 20 mg/kg bodyweight of nanoparticles in mice.
EXP | Group | Bodyweight gain | Liver | Spleen | Kidney |
---|---|---|---|---|---|
1 | Vehicle (0.9% NaCl) | -1.6 ± 1.9 | 6.6 ± 1.2 | 0.5 ± 0.1 | 1.9 ± 0.0 |
|
Fe3O4-DAAO 100 mg/kg |
-3.5 ± 2.2 |
7.8 ± 0.3 |
0.6 ± 0.1 |
1.6 ± 0.1 |
2 | Vehicle (NaPPi) | -2.9 ± 0.4 | 6.7 ± 0.1 | 0.5 ± 0.1 | 1.8 ± 0.1 |
Fe3O4-DAAO 20 mg/kg | -3.5 ± 2.8 | 6.9 ± 0.2 | 0.5 ± 0.1 | 1.6 ± 0.2 |
Results are expressed as means ± SD.